Please use this identifier to cite or link to this item:
|Title:||Cardiovascular risk factors in non-insulin-dependent diabetics compared to non-diabetic controls: A population-based survey among Asians in Singapore|
|Authors:||Hughes, K. |
|Source:||Hughes, K., Ong, C.-N., Choo, M., Kuperan, P., Aw, T.-C. (1998). Cardiovascular risk factors in non-insulin-dependent diabetics compared to non-diabetic controls: A population-based survey among Asians in Singapore. Atherosclerosis 136 (1) : 25-31. ScholarBank@NUS Repository. https://doi.org/10.1016/S0021-9150(97)00180-9|
|Abstract:||Cardiovascular risk factors were compared between 126 people with non- insulin-dependent diabetes mellitus (NIDDM) and 530 non-diabetics (controls), in a random sample of people (Chinese, Malays, and Asian Indians) aged 40-69 years from the general population of Singapore. Data were adjusted for age and ethnicity. For both genders, people with NIDDM had higher mean body mass indices, waist-hip ratios and abdominal diameters. They also had a higher prevalence of hypertension, higher mean levels of fasting serum triglyceride, slightly lower mean levels of serum high-density-lipoprotein cholesterol, and higher mean levels of plasma plasminogen activator inhibitor-1 and tissue plasminogen activator (antigen). These factors are components of syndrome X (metabolic syndrome) and increase the risk of atherosclerosis and thrombosis. In contrast, there were no important differences for cigarette smoking, serum total and low-density-lipoprotein cholesterol, serum apolipoproteins A1 and B, plasma factor VIIc and plasma prothrombin fragment 1 + 2. Females with NIDDM, but not males, had a higher mean serum fibrinogen level than non- diabetics, which could explain why NIDDM has a greater cardiovascular effect in females than males. Serum lipoprotein(a) concentrations were lower in people with NIDDM. Mean levels of serum ferritin, a pro-oxidant, were higher in people with NIDDM than controls, but there were no important differences for plasma vitamins A, C and E, and serum selenium, which are anti-oxidants.|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Mar 7, 2018
WEB OF SCIENCETM
checked on Feb 5, 2018
checked on Mar 11, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.