Please use this identifier to cite or link to this item:
|Title:||Separation of globins using free zone capillary electrophoresis|
|Authors:||Ong, C.-N. |
|Source:||Ong, C.-N., Liau, L.S., Ong, H.Y. (1992). Separation of globins using free zone capillary electrophoresis. Journal of Chromatography - Biomedical Applications 576 (2) : 346-350. ScholarBank@NUS Repository. https://doi.org/10.1016/0378-4347(92)80210-H|
|Abstract:||This paper describes the use of high-performance capillary electrophoresis for the separation of globin chains. Adult and newborn haemolysates from normal individuals and children suspected of having thalassaemia were analysed using free zone electrophoresis. Separation of globins was accomplished using a 25 μM phosphate buffer at pH 11.8. Distinct peaks of α-, β- and γ-chains were resolved within 8 min. The coefficient of variation for within-day and between-day runs was 4.1% and 5.7%, respectively. This method is simple and rapid, and it can be used to screen for thalassaemia and for the clinical study of various haemoglobinopathies.|
|Source Title:||Journal of Chromatography - Biomedical Applications|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Mar 7, 2018
WEB OF SCIENCETM
checked on Jan 30, 2018
checked on Mar 11, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.