Please use this identifier to cite or link to this item:
https://scholarbank.nus.edu.sg/handle/10635/29031
DC Field | Value | |
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dc.title | Influence of gender and age at onset on the HLA associations in Chinese with insulin-dependent diabetes mellitus | |
dc.contributor.author | Chan, S.H. | |
dc.contributor.author | Wee, G.B. | |
dc.contributor.author | Thai, A.C. | |
dc.contributor.author | Liu, K.F. | |
dc.contributor.author | Lin, Y.N. | |
dc.date.accessioned | 2011-11-29T09:15:42Z | |
dc.date.available | 2011-11-29T09:15:42Z | |
dc.date.issued | 1995 | |
dc.identifier.citation | Chan, S.H., Wee, G.B., Thai, A.C., Liu, K.F., Lin, Y.N. (1995). Influence of gender and age at onset on the HLA associations in Chinese with insulin-dependent diabetes mellitus. Human Immunology 44 (3) : 175-180. ScholarBank@NUS Repository. | |
dc.identifier.issn | 01988859 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/29031 | |
dc.description.abstract | IDDM in Singaporean Chinese was associated with HLA B58, DRB1*0301, DQB1*0201, and joint occurrences of DRB1*0301/*0901 and DRB1*0301/*04. Of the DR4s the frequencies of DRB1*0401, *0404, and *0405 were higher and *0406 was lower in patients compared to controls. DRB*0301/*0901 was observed mainly in female patients and the frequency showed an inverse relationship with age at onset, whereas DRB1*0301/*04 was observed mainly in male patients and also showed an inverse relationship with age at onset. DRB1*1202 showed an increasing frequency with age at onset. IDDM patients had a higher frequency of homozygous NAsp57 DQβ chains and a lower frequency of homozygous Asp57 DQβ chains compared to controls, especially in younger onset patients. | |
dc.description.uri | http://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/0198-8859(95)00085-2 | |
dc.source | Scopus | |
dc.type | Article | |
dc.contributor.department | WHO IMMUNOLOGY RESEARCH & TRAINING CTR | |
dc.contributor.department | MEDICINE | |
dc.contributor.department | MICROBIOLOGY | |
dc.description.sourcetitle | Human Immunology | |
dc.description.volume | 44 | |
dc.description.issue | 3 | |
dc.description.page | 175-180 | |
dc.description.coden | HUIMD | |
dc.identifier.isiut | A1995TK54100007 | |
Appears in Collections: | Staff Publications |
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