Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.bbamcr.2005.02.007
Title: COPII and exit from the endoplasmic reticulum
Authors: Bor, L.T. 
Wang, Y. 
Yan, S.O.
Hong, W. 
Keywords: Coat protein II
Endoplasmic reticulum
Golgi
Sar1
Sec13/31
Sec24
Issue Date: 2005
Source: Bor, L.T., Wang, Y., Yan, S.O., Hong, W. (2005). COPII and exit from the endoplasmic reticulum. Biochimica et Biophysica Acta - Molecular Cell Research 1744 (3 SPEC. ISS.) : 293-303. ScholarBank@NUS Repository. https://doi.org/10.1016/j.bbamcr.2005.02.007
Abstract: First discovered by genetic analysis of yeast secretion mutants, the evolutionarily conserved vesicular coat protein II (COPII) complex is responsible for membrane transport from the endoplasmic reticulum (ER) to the Golgi apparatus. In recent years, extensive efforts in structural, morphological, genetic and molecular analysis have greatly enhanced our understanding of the structural and molecular basis of COPII subunit assembly and selective cargo packaging during ER export. Very recent data have also indicated that a more "classical" picture of vesicle formation from ER exit sites (ERES) followed by their transport to the Golgi is far from accurate. Proteins modulating the function of COPII have also emerged in recent analysis. They either affect COPII-based cargo selection, the formation of vesicle/transport carrier, or subsequent targeting of the transport carrier. Together, elucidation of COPII-mediated ER export has painted a fascinating picture of molecular complexity for an essential process in all eukaryotic cells. © 2005 Elsevier B.V. All rights reserved.
Source Title: Biochimica et Biophysica Acta - Molecular Cell Research
URI: http://scholarbank.nus.edu.sg/handle/10635/28740
ISSN: 01674889
DOI: 10.1016/j.bbamcr.2005.02.007
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

60
checked on Jan 8, 2018

WEB OF SCIENCETM
Citations

54
checked on Jan 8, 2018

Page view(s)

123
checked on Jan 15, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.