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Title: Atlas-assisted segmentation of hippocampus
Keywords: Hippocampus, MRI, segmentation, Talairach transformation, Modified Talairach Landmarks
Issue Date: 12-Jan-2006
Source: PHAM DUC MINH (2006-01-12). Atlas-assisted segmentation of hippocampus. ScholarBank@NUS Repository.
Abstract: The hippocampus is a small gray matter structure that is adjacent to other gray matter structures e.g amygdala, parahippocampus gyrus. The hippocampus has no clearly distinguishable boundaries along significant portion of its surface . That is why segmentation of hippocampus from its neighbors is still a challenge of medical image processing. I propose an atlas-assisted method to segment the hippocampus in brain MR neuroimages. The method is implemented in two steps: global and local. In the global step, the initial location of the hippocampus is determined by a brain atlas registered with the scan. For registration, we use the modified Talairach transformation based on the midsagittal plane, anterior and posterior commissures, and the extents of the brain. In the local step, this coarse segmentation is refined locally of applying active contours with anatomical knowledge constraints.
Appears in Collections:Master's Theses (Open)

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