Please use this identifier to cite or link to this item:
|Title:||Central Corneal Thickness and its Associations With Ocular and Systemic Factors: The Singapore Malay Eye Study|
|Citation:||Su, D.H.W., Wong, T.Y., Tay, W.-T., Saw, S.-M., Aung, T., Foster, P.J. (2009). Central Corneal Thickness and its Associations With Ocular and Systemic Factors: The Singapore Malay Eye Study. American Journal of Ophthalmology 147 (4). ScholarBank@NUS Repository. https://doi.org/10.1016/j.ajo.2008.10.013|
|Abstract:||Purpose: To examine the association between central corneal thickness (CCT) and potential systemic and ocular factors affecting CCT in an Asian population. Design: Population-based cross-sectional study. Methods: A total of 3,280 (78.7% response) adults aged 40 to 80 years of Malay ethnicity living in Singapore underwent a standardized interview and ocular and systemic examination at a centralized study clinic. CCT was measured with an ultrasound pachymeter. Blood samples were obtained to determine serum glucose, cholesterol, and triglyceride levels, and urine samples to determine glomerular filtration rate. The presence of diabetes, hypertension, chronic kidney disease (CKD), and metabolic syndrome were defined based on a combination of investigation results and participant's history. Results: CCT was obtained from 3,239 individuals. CCT was normally distributed with a mean of 541.2 μm in the right eye. While controlling for age and gender, CCT was greater in individuals with higher body mass index (BMI) (P = .038), greater intraocular pressure (IOP) (P < .001), greater axial length (P = .005), and greater radius of corneal curvature (P < .001). Individuals with CKD (P = 0.012) and metabolic syndrome (P < .001) also had greater CCT. Conclusion: CCT is associated with higher IOP, longer axial length, and greater radius of corneal curvature, as well as higher BMI, metabolic syndrome, and CKD. © 2009 Elsevier Inc. All rights reserved.|
|Source Title:||American Journal of Ophthalmology|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Feb 13, 2019
WEB OF SCIENCETM
checked on Feb 13, 2019
checked on Feb 3, 2019
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.