Please use this identifier to cite or link to this item:
|Title:||Correlation between MR imaging-derived nasopharyngeal carcinoma tumor volume and TNM system|
|Authors:||Chong, V.F.H. |
|Keywords:||Magnetic resonance tumor volume measurement|
|Citation:||Chong, V.F.H., Zhou, J.-Y., Chan, K.-L., Khoo, J.B.K., Huang, J. (2006). Correlation between MR imaging-derived nasopharyngeal carcinoma tumor volume and TNM system. International Journal of Radiation Oncology Biology Physics 64 (1) : 72-76. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ijrobp.2005.06.027|
|Abstract:||Purpose: To measure nasopharyngeal carcinoma tumor volume based on magnetic resonance images using a validated semiautomated measurement methodology and correlate tumor volume with TNM T classification. Methods and Materials: The study population consisted of 206 consecutive nasopharyngeal carcinoma patients who had magnetic resonance imaging staging scans. Tumor volume was measured using a semisupervised knowledge-based fuzzy clustering algorithm. Patients were divided into 4 groups according to TNM T classification. The difference in tumor volumes among the various TNM T-classification groups was examined. Results: The mean tumor volume in each T-classification group is as follows: T1, 8.6 mL ± 5.0 (standard deviation [SD]); T2, 18.1 mL ± 8.1 (SD); T3, 25.8 mL ± 14.1 (SD); and T4, 36.2 mL ± 18.9 (SD). The mean tumor volume increased significantly with advancing T classification (p < 0.0001). Tumor volume in a more advanced T group was significantly larger than that in an adjacent early T group (p < 0.01). Conclusion: Validated magnetic resonance imaging-based tumor volume shows positive correlation between tumor volume and advancing T-classification groups. It may be possible to incorporate tumor volume as an additional prognostic factor into the existing TNM system. © 2006 Elsevier Inc.|
|Source Title:||International Journal of Radiation Oncology Biology Physics|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Sep 13, 2018
WEB OF SCIENCETM
checked on Sep 4, 2018
checked on Jul 13, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.