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https://doi.org/10.1167/tvst.9.13.12
Title: | Annual Myopia Progression and Subsequent 2-Year Myopia Progression in Singaporean Children | Authors: | Matsumura, Saiko Lanca, Carla Htoon, Hla Myint Brennan, Noel Tan, Chuen-Seng Kathrani, Biten Chia, Audrey Tan, Donald Sabanayagam, Charumathi Saw, Seang-Mei |
Keywords: | Science & Technology Life Sciences & Biomedicine Ophthalmology myopia progression age at baseline children SCHOOL-CHILDREN REFRACTIVE ERROR VISUAL IMPAIRMENT URBAN CHILDREN RISK-FACTORS PREVALENCE SCHOOLCHILDREN NEARWORK |
Issue Date: | 1-Dec-2020 | Publisher: | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Citation: | Matsumura, Saiko, Lanca, Carla, Htoon, Hla Myint, Brennan, Noel, Tan, Chuen-Seng, Kathrani, Biten, Chia, Audrey, Tan, Donald, Sabanayagam, Charumathi, Saw, Seang-Mei (2020-12-01). Annual Myopia Progression and Subsequent 2-Year Myopia Progression in Singaporean Children. TRANSLATIONAL VISION SCIENCE & TECHNOLOGY 9 (13). ScholarBank@NUS Repository. https://doi.org/10.1167/tvst.9.13.12 | Abstract: | Purpose: To investigate the association between 1-year myopia progression and subsequent 2-year myopia progression among myopic children in the Singapore Cohort Study of the Risk Factors for Myopia. Methods: This retrospective analysis included 618 myopic children (329 male), 7 to 9 years of age (mean age, 8.0 ± 0.8) at baseline with at least two annual follow-up visits. Cycloplegic autorefraction was performed at every visit. Receiver operating characteristic (ROC) curves from multiple logistic regressions were derived for future fast 2-year myopia progression. Results: Children with slow progression during the first year (slower than –0.50 diopter [D]/y) had the slowest mean subsequent 2-year myopia progression (–0.41 ± 0.33 D/y), whereas children with fast progression (faster than –1.25 D/y) in year 1 had the fastest mean subsequent 2-year myopia progression (–0.82 ± 0.30 D/y) (P for trend < 0.001). Year 1 myopia progression had the highest area under the curve (AUC) for predicting fast subsequent 2-year myopia progression (AUC = 0.77; 95% confidence interval [CI], 0.73–0.80) compared to baseline spherical equivalent (AUC = 0.70; 95% CI, 0.66–0.74) or age of myopia onset (AUC = 0.66; 95% CI, 0.61–0.70) after adjusting for confounders. Age at baseline alone had an AUC of 0.65 (95% CI, 0.61–0.69). Conclusions: One-year myopia progression and age at baseline were associated with subsequent 2-year myopia progression in children 7 to 9 years of age. Translational Relevance: Myopia progression and age at baseline may be considered by eye care practitioners as two of several factors that may be associated with future myopia progression in children. | Source Title: | TRANSLATIONAL VISION SCIENCE & TECHNOLOGY | URI: | https://scholarbank.nus.edu.sg/handle/10635/242005 | ISSN: | 2164-2591,2164-2591 | DOI: | 10.1167/tvst.9.13.12 |
Appears in Collections: | Staff Publications Elements |
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