Please use this identifier to cite or link to this item:
https://doi.org/10.1007/978-3-031-07634-3_16
DC Field | Value | |
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dc.title | Epigenetic Small-Molecule Modulators Targeting Metabolic Pathways in Cancer | |
dc.contributor.author | Das, D | |
dc.contributor.author | Karthik, N | |
dc.contributor.author | Taneja, R | |
dc.date.accessioned | 2022-11-22T03:13:59Z | |
dc.date.available | 2022-11-22T03:13:59Z | |
dc.date.issued | 2022-01-01 | |
dc.identifier.citation | Das, D, Karthik, N, Taneja, R (2022-01-01). Epigenetic Small-Molecule Modulators Targeting Metabolic Pathways in Cancer. Subcell Biochem 100 : 523-555. ScholarBank@NUS Repository. https://doi.org/10.1007/978-3-031-07634-3_16 | |
dc.identifier.issn | 0306-0225 | |
dc.identifier.issn | 2542-8810 | |
dc.identifier.uri | https://scholarbank.nus.edu.sg/handle/10635/234745 | |
dc.description.abstract | Metabolic deregulation is a key factor in cancer progression. Epigenetic changes and metabolic rewiring are intertwined in cancer. Deregulated epigenetic modifiers cause metabolic aberrations by targeting the expression of metabolic enzymes. Conversely, metabolites and cofactors affect the expression and activity of epigenetic regulators. Small molecules are promising therapeutic approaches to target the epigenetic-metabolomic crosstalk in cancer. Here, we focus on the interplay between metabolic rewiring and epigenetic landscape in the context of tumourigenesis and highlight recent advances in the use of small-molecule drug targets for therapy. | |
dc.publisher | Springer International Publishing | |
dc.source | Elements | |
dc.subject | Cancer | |
dc.subject | Epigenetics | |
dc.subject | Metabolism | |
dc.subject | Signalling pathways | |
dc.subject | Small molecules | |
dc.subject | Humans | |
dc.subject | Neoplasms | |
dc.subject | Epigenomics | |
dc.subject | Epigenesis, Genetic | |
dc.subject | Metabolic Networks and Pathways | |
dc.type | Article | |
dc.date.updated | 2022-11-21T06:31:30Z | |
dc.contributor.department | PHYSIOLOGY | |
dc.description.doi | 10.1007/978-3-031-07634-3_16 | |
dc.description.sourcetitle | Subcell Biochem | |
dc.description.volume | 100 | |
dc.description.page | 523-555 | |
dc.published.state | Published | |
Appears in Collections: | Staff Publications Elements |
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Das et al revised 04062021.pdf | 1.75 MB | Adobe PDF | OPEN | None | View/Download |
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