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https://doi.org/10.1093/scan/nsz060
Title: | The 5-HTTLPR polymorphism impacts moral permissibility of impersonal harmful behaviors | Authors: | Yang, Y. Wang, C. Li, X. Yu, R. Zhang, M. Xue, M. Guo, W. He, L. Gao, X. Gong, P. |
Keywords: | cross-sectional analysis impersonal harm moral judgment personal harm serotonin transporter gene two-wave comparison |
Issue Date: | 2019 | Publisher: | Oxford University Press | Citation: | Yang, Y., Wang, C., Li, X., Yu, R., Zhang, M., Xue, M., Guo, W., He, L., Gao, X., Gong, P. (2019). The 5-HTTLPR polymorphism impacts moral permissibility of impersonal harmful behaviors. Social Cognitive and Affective Neuroscience 14 (8) : 911-918. ScholarBank@NUS Repository. https://doi.org/10.1093/scan/nsz060 | Rights: | Attribution-NonCommercial-NoDerivatives 4.0 International | Abstract: | Inspired by the roles of serotonin in an emotional aversion to harmful actions, we examined to what extent serotonin transporter gene (5-HTT)-linked polymorphic region (5-HTTLPR), a proxy for measuring serotonin function, underpinned the individual differences in moral judgment through cross-sectional analysis and two-wave comparison. The cross-sectional analysis with a larger cohort (N = 1197) showed that the SS carriers of the 5-HTTLPR polymorphism, corresponding to the low ratio of serotonin recycling from the synaptic cleft, rated impersonal harmful actions (e.g. flipping a switch to divert a train to hit one person instead of five people) as more permissible as compared with the L-allele carriers. The two-wave comparison with a subsample from the larger cohort (N = 563) indicated that the association between 5-HTTLPR polymorphism and moral permissibility of impersonal harmful actions was stable from wave 1 to wave 2. Thus, these findings highlight the importance of the 5-HTTLPR polymorphism to harmful moral behaviors. � 2019 The Author(s) 2019. Published by Oxford University Press. | Source Title: | Social Cognitive and Affective Neuroscience | URI: | https://scholarbank.nus.edu.sg/handle/10635/212935 | ISSN: | 17495016 | DOI: | 10.1093/scan/nsz060 | Rights: | Attribution-NonCommercial-NoDerivatives 4.0 International |
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