Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/17733
Title: Estimation of Central Retinal Vascular Equivalent: Canonical Correlation Analysis
Authors: WANG LING
Keywords: blood pressures, SiMES, CRAE, CRVE, multiple linear regression analysis, canonical correlation analysis
Issue Date: 9-Feb-2010
Source: WANG LING (2010-02-09). Estimation of Central Retinal Vascular Equivalent: Canonical Correlation Analysis. ScholarBank@NUS Repository.
Abstract: Hypertension, obesity, diabetes and retinopathy are common health problems in the world. A quantitative assessment in retinal microvascular caliber may provide information to the risks of these systematic health problems. The Singapore Malay Eye Study (SiMES) was a population-based cross-sectional study in Singapore. Diastolic blood pressure (dbpdia), systolic blood pressure (dbpsys), body mass index (BMI), glucose, all retinal arterioles and venules diameters were measured for all participants in the study. The purpose of this study is to use the statistical methods to quantify the central retinal arteriole (or venule) equivalent (CRAE or CRVE) . Multiple linear regression analysis and canonical correlation analysis (CCA) had been applied to estimate CRAE such that the Pearson correlations between CRAE and dbpdia, dbpsys, BMI and glucose were maximized, respectively. The results showed that the CCA was more appropriate to quantify CRAE in this study.
URI: http://scholarbank.nus.edu.sg/handle/10635/17733
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