Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/17681
Title: Fast time-domain diffuse optical tomography for breast tissue characterization and imaging
Authors: MO WEIRONG
Keywords: Time-resolved imaging, Medical optics instruments, Photon migration, Tomography
Issue Date: 22-Sep-2006
Source: MO WEIRONG (2006-09-22). Fast time-domain diffuse optical tomography for breast tissue characterization and imaging. ScholarBank@NUS Repository.
Abstract: Near-infrared (NIR) diffuse optical tomography (DOT) has been proven in last decade as a promising non-invasive optical imaging modality for soft tissue imaging, especially suitable for human breast imaging. This research aims to explore the feasibility of a novel tomographic imager to characterize the optical properties of human breast tissue in vivo. The innovation of this approach is to use a high speed pseudorandom bit sequence (PRBS) to acquire the time-resolved signals or the temporal point spread functions (TPSF). The prototype system was constructed. Its performance was assessed in phantom experiments. Furthermore, the prototype system was used to characterize the optical properties and physiological parameters of human breast tissues in vivo. Correlations between optical properties, physiological parameters of the breast tissue and the demographic factors (age, menopausal state and body mass index) were established. The preliminary in vivo results are promising. The prototype
URI: http://scholarbank.nus.edu.sg/handle/10635/17681
Appears in Collections:Ph.D Theses (Open)

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