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Title: Risk estimation in retrospective studies
Authors: WEI XING
Keywords: risk, case-control study, odds ratio, prevalence, Bayes' theorem
Issue Date: 23-Nov-2009
Citation: WEI XING (2009-11-23). Risk estimation in retrospective studies. ScholarBank@NUS Repository.
Abstract: The analysis of data arising from retrospective studies traditionally followed methods<br>involving estimation of relative risks and/or odds ratios. Little attention was given to<br>estimation of risks, presumably due to constraint of such experimental designs, as well<br>as the ease of modelling of odds ratio by logistic regression. Here we present some<br>results for the estimation of risks in a general 2 by k contingency table setting, for a<br>dichotomous outcome variable and under some reasonable assumption of prevalence.<br>We also examine the properties of proposed estimators, and apply them to a largescale<br>genome-wide association (GWA) study data to demonstrate some relevance of the<br>methods.
Appears in Collections:Master's Theses (Open)

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