Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/16562
Title: Engineering Soluble Microenvironments in Microfluidic Systems
Authors: ZHANG CHI
Keywords: microenvironment, microfluidic, cell culture, soluble factor, toxicity, pharmacokinetics
Issue Date: 29-Jul-2009
Source: ZHANG CHI (2009-07-29). Engineering Soluble Microenvironments in Microfluidic Systems. ScholarBank@NUS Repository.
Abstract: Highly functional in vitro cultured cells are of great usefulness in various applications such as cell-based testing, constructing large tissues and pathological research. The key to culturing functional cells in vitro is to recapitulate an in vivo-like cellular microenvironment which allows extensive mechanical support as well as cell-cell, cell-matrix and cell-soluble factor interactions. This thesis demonstrates the strategy of engineering soluble microenvironments in microfluidic cell culture systems for various cell types, which significantly enhanced the biological functions of either primary cells or cell lines. It can be potentially used as a general drug testing platform.
URI: http://scholarbank.nus.edu.sg/handle/10635/16562
Appears in Collections:Ph.D Theses (Open)

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
zhang chi_phd_NGS_engineering soluble microenvironments in microfluidic devices_2009.pdf3.82 MBAdobe PDF

OPEN

NoneView/Download

Page view(s)

290
checked on Jan 11, 2018

Download(s)

304
checked on Jan 11, 2018

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.