Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/16378
Title: Ethnic differences in the effect of parity on breast cancer incidence in premenopausal women in Singapore
Authors: YAP PENG LENG, KAREN
Keywords: Breast Cancer, Epidemiology, Singapore, Ethnic, Premenopausal
Issue Date: 9-Feb-2009
Source: YAP PENG LENG, KAREN (2009-02-09). Ethnic differences in the effect of parity on breast cancer incidence in premenopausal women in Singapore. ScholarBank@NUS Repository.
Abstract: Differences in the effect of multiparity on breast cancer risk exist in Caucasian, African-American and Hispanic women. Studies in Asian populations are lacking. This thesis proposes that ethnic differences exist in the effect of multiparity on breast cancer incidence in pre-menopausal women in the three major ethnic groups in Singapore. By linkage between the Singapore National Registry of Births and Deaths and the Singapore Cancer Registry, we identified 228,419 mothers, of whom 523 had breast cancer. Through multivariate Cox analysis, the relationship between ethnicity, parity and premenopausal breast cancer risk was examined, adjusted for age at first and last childbirth. The effect of parity on breast cancer risk was shown to be modified by ethnicity. The risk was highest in uniparous Malay women (hazard ratio 1.91 relative to Chinese) and lowest in Indians (HR 0.38). Increased parity reduced the risk in Malays but not in Chinese and Indian women.
URI: http://scholarbank.nus.edu.sg/handle/10635/16378
Appears in Collections:Master's Theses (Open)

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
Yap PLK.pdf3.84 MBAdobe PDF

OPEN

NoneView/Download

Page view(s)

227
checked on Dec 11, 2017

Download(s)

159
checked on Dec 11, 2017

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.