Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/16238
Title: A NUMERICAL STUDY OF SWIRLING FLOW AND OXYGEN TRANSPORT IN A MICRO-BIOREACTOR
Authors: YU PENG
Keywords: swirling flow, micro-bioreactor, porous-fluid interface, porous scaffold, stress jump, oxygen transport
Issue Date: 3-May-2007
Source: YU PENG (2007-05-03). A NUMERICAL STUDY OF SWIRLING FLOW AND OXYGEN TRANSPORT IN A MICRO-BIOREACTOR. ScholarBank@NUS Repository.
Abstract: A numerical model was developed for a micro-bioreactor, of working volume around a few millilitres, in which the medium was mixed by a magnetic stirrer rod at the base. The flow pattern in the micro-bioreactor was found to resemble swirling flow with vortex breakdown. To examine the conditions for vortex breakdown, the swirling flow in an enclosed cylinder with a partially rotating bottom-wall was modeled. The cylinder-to disk ratio, up to 1.6, is found to have noticeable effect on vortex breakdown. In order to model a micro-bioreactor which has a porous scaffold, a numerical method was developed to simulate the flow conditions at a fluid-porous interface. A numerical model was developed for the flow and mass transport around and through a porous scaffold in the micro-bioreactor. The results show that the Reynolds number and the Darcy number have noticeable effects on the flow and oxygen concentration within the scaffold.
URI: http://scholarbank.nus.edu.sg/handle/10635/16238
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