Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/16135
Title: Pharmacoeconomics and health outcomes research for Hepatitis B virus infection in Singapore
Authors: ONG SIEW CHIN
Keywords: Pharmacoeconomics, health outcomes research, chronic hepatitis B infection, health-related quality of life, cost-of-illness, cost-effectiveness
Issue Date: 28-Jun-2007
Source: ONG SIEW CHIN (2007-06-28). Pharmacoeconomics and health outcomes research for Hepatitis B virus infection in Singapore. ScholarBank@NUS Repository.
Abstract: The current thesis reported the results of application of pharmacoeconomic and outcomes principles in evaluating the management of hepatitis B virus (HBV) infection in Singapore to quantify the clinical and economic impact of the disease. There are several findings: 1. Health status (measured by health-related quality of life instruments) of HBV patients with early disease stage have scores comparable with those of healthy controls; and the disease affects patientsa?? mental domain more adversely than the physical domain. 2. The Hepatitis Quality of Life Questionnaire would be a valid and reliable tool to be used in HBV patient. 3. Our economic studies provided evidence that the cost of management for HBV disease is substantial and lamivudine as the most cost-effective antiviral currently for the initial phase of infection. Our results would therefore be informative to the healthcare planner/provider in the management and prioritization of resource of HBV infection.
URI: http://scholarbank.nus.edu.sg/handle/10635/16135
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