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Title: A study on the kinetics of the reaction between chlorpromazine cation radical and pyrogallol
Keywords: chlorpromazine cation radical, kinetics, mechanism, antiradical activity
Issue Date: 15-Jun-2009
Citation: SEYEDEH FATEMEH SEYEDREIHANI (2009-06-15). A study on the kinetics of the reaction between chlorpromazine cation radical and pyrogallol. ScholarBank@NUS Repository.
Abstract: The most important characteristic of an antioxidant is its ability to trap free radicals. Recently phenothiazine-based cation radicals have been in significant interest.Although chlorpromazine cation radical shows similar characteristics such as being colored for colorimetric methods and self-stabilization to those of ABTS and DPPH, there are no much studies to test if chlorpromazine cationic radical can be used as a free radical in radical scavenging methods to detect the antioxidant activity. In this study the most popular methods for determining antioxidant activity is reviewed. In following, kinetic and mechanism of the reaction of chlorpromazine cation radical with pyrogallol which is a phenolic antioxidant is investigated by using two methods; Method of initial rates and a proposed computational method. Thereafter, the results of both methods are tabulated, discussed and compared.
Appears in Collections:Master's Theses (Open)

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