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Title: Finite element modeling of human brain and application in neurosurgical procedures
Keywords: Model; brain atlas; deformation; mesh; finite element method; surgical intervention
Issue Date: 13-Feb-2007
Citation: GAO CHUNPING (2007-02-13). Finite element modeling of human brain and application in neurosurgical procedures. ScholarBank@NUS Repository.
Abstract: This thesis presents the development of a biomechanical model of the human brain to investigate brain deformation under surgical conditions. A physics-based brain atlas is constructed to connect the finite element framework with the atlas assisted analysis. This atlas with associated meshes consists of 44 brain structures to account for the salient anatomical features. Typical element types of the atlas have been generated in a multiple-object fashion. The mechanical model integrated into this atlas is characterized by generalizing experimental data that suits the loading conditions consistent with surgical settings. To validate its utility in surgical applications, finite element simulations of typical brain deformation cases have been performed with various strain rates. The atlas model reproduces complex brain deformation phenomena induced by craniotomy and ventriculoperitoneal shunting. This modelling approach enables a more realistic and informative representation of brain deformation during surgical intervention by providing insights into the subcortical brain behaviours.
Appears in Collections:Ph.D Theses (Open)

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