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Title: National survey of outcomes and practices in acute respiratory distress syndrome in Singapore
Authors: Siddiqui S.
Puthucheary Z.
Phua J.
Ho B.
Tan J.
Chuin S.
Lim N.L.
Soh C.R.
Loo C.M.
Tan A.Y.H.
Mukhopadhyay A.
Khan F.A.
Johan A.
Tan A.H.
Maclaren G. 
Taculod J.
Ramos B.
Han T.A.
Cove M.E.
Issue Date: 16-Jun-2017
Publisher: Public Library of Science
Citation: Siddiqui S., Puthucheary Z., Phua J., Ho B., Tan J., Chuin S., Lim N.L., Soh C.R., Loo C.M., Tan A.Y.H., Mukhopadhyay A., Khan F.A., Johan A., Tan A.H., Maclaren G., Taculod J., Ramos B., Han T.A., Cove M.E. (2017-06-16). National survey of outcomes and practices in acute respiratory distress syndrome in Singapore. PLoS ONE 12 (6) : e0179343. ScholarBank@NUS Repository.
Abstract: Introduction In the past 20 years, our understanding of acute respiratory distress syndrome (ARDS) management has improved, but the worldwide incidence and current outcomes are unclear. The reported incidence is highly variable, and no studies specifically characterise ARDS epidemiology in Asia. This observation study aims to determine the incidence, mortality and management practices of ARDS in a high income South East Asian country. Methods We conducted a prospective, population based observational study in 6 public hospitals. During a one month period, we identified all ARDS patients admitted to public hospital intensive care units (ICU) in Singapore, according to the Berlin definition. Demographic information, clinical management data and ICU outcome data was collected. Results A total of 904 adult patients were admitted to ICU during the study period and 15 patients met ARDS criteria. The unadjusted incidence of ARDS was 4.5 cases per 100,000 population, accounting for 1.25% of all ICU patients. Most patients were male (75%), Chinese (62%), had pneumonia (73%), and were admitted to a Medical ICU (56%). Management strategies varied across all ICUs. In-hospital mortality was 40% and median length of ICU stay was 7 days. Conclusion The incidence of ARDS in a developed S.E Asia country is comparable to reported rates in European studies. � 2017 Siddiqui et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Source Title: PLoS ONE
ISSN: 19326203
DOI: 10.1371/journal.pone.0179343
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