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Title: | CANCER IMMUNOGENE THERAPY USING VIRAL VECTORS ENCODING CYTOKINES AND CHIMERIC ANTIGEN RECEPTORS | Authors: | ANG WEI XIA | Keywords: | baculovirus, immunogene therapy, car | Issue Date: | 7-Dec-2017 | Citation: | ANG WEI XIA (2017-12-07). CANCER IMMUNOGENE THERAPY USING VIRAL VECTORS ENCODING CYTOKINES AND CHIMERIC ANTIGEN RECEPTORS. ScholarBank@NUS Repository. | Abstract: | Cancer immunotherapy enhances the functions of a patient’s immune cells to recognise cancer antigens and attack cancer cells, and it is currently one of the most promising cancer treatment approaches. This thesis explores three types of cancer immunotherapies: (i) baculovirus-mediated immunogene therapy with baculoviral vector, (ii) anti-epithelial cell adhesion molecule (EpCAM) chimeric antigen receptor (CAR)-grafted T cell therapy, and (iii) natural-killer group 2, member D (NKG2D) CAR-grafted T cell therapy. | URI: | http://scholarbank.nus.edu.sg/handle/10635/146564 |
Appears in Collections: | Ph.D Theses (Open) |
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