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Title: Dyslipidemia in systemic lupus erythematosus
Keywords: SLE, hyperlipidemia, premature atherosclerosis, corticosteroids, nephritic syndrome, active lupus
Issue Date: 7-May-2005
Citation: LEONG KENG HONG (2005-05-07). Dyslipidemia in systemic lupus erythematosus. ScholarBank@NUS Repository.
Abstract: Systemic Lupus Erythematosus (SLE) is an illness with a poor prognosis in the past. In recent years, treatment options have improved and patients often survive more than ten years from the time of diagnosis. This has given rise to new problems related to organ damage and long term side effects of medications. One of these problems which only recently has been recognised is dyslipidemia.In a study of Singaporean SLE patients with a mean age of 32, 35% had severe lipid abnormalities of high LDL, high TG, low HDL and abnormal TC/HDL ratios. Hyperlipidemia in SLE is associated with the presence of nephrotic syndrome, active lupus and the use of systemic corticosteroids. To prevent the onset of atherosclerotic complications hyperlipidemia in SLE patients should be diagnosed early and treated accordingly.
Appears in Collections:Ph.D Theses (Open)

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