Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/145857
Title: FACTORS CONTRIBUTING TO HOSPITAL-ACQUIRED HYPOGLYCAEMIA IN TYPE 2 DIABETES MELLITUS ELDERLY PATIENTS IN AN ACUTE HOSPITAL IN SINGAPORE: A RETROSPECTIVE STUDY
Authors: LEE JUE LEI DAPHNE
Keywords: hypoglycaemia, type 2 diabetes mellitus, non-insulin dependent diabetes mellitus, elderly, hospital-acquired, inpatients, contributing factors, risk factors, predisposing factors and causes.
Issue Date: 21-Jun-2018
Citation: LEE JUE LEI DAPHNE (2018-06-21). FACTORS CONTRIBUTING TO HOSPITAL-ACQUIRED HYPOGLYCAEMIA IN TYPE 2 DIABETES MELLITUS ELDERLY PATIENTS IN AN ACUTE HOSPITAL IN SINGAPORE: A RETROSPECTIVE STUDY. ScholarBank@NUS Repository.
Abstract: Aims and Objectives: To explore the demographic and clinical factors which affect hypoglycaemic severity and risks, specific to Singapore’s multi-ethnic population. Background: Hypoglycaemia is a common complication in blood glucose management in Type 2 Diabetes Mellitus (T2DM) patients and has a high prevalence in the elderly, however, limited local clinical studies have been conducted to explore its contributing factors. As hypoglycaemia can result in adverse physiological and economic burden if not managed adequately, knowledge is required to be built on to reduce hypoglycaemic severity. Findings will value-add to Diabetes Mellitus care provision. Methods: A quantitative retrospective chart review was conducted to identify patients with T2DM admitted in general wards from 1st May 2016 through 31st May 2017, with capillary blood glucose levels ? 3.9mmol/L. Opportunistic sampling was used to recruit the minimum sample size of patients fulfilling recruitment criteria, whose medical records were retrieved. Data were abstracted using the Clinical Data Collection Form, and analysed with parametric tests. Statistical significance was set at P-value < 0.05. Results: Data from a total of 245 electronic medical records were reviewed and collected. Univariate analyses showed statistical significance between hypoglycaemic severity and total number of non-antidiabetic medications (P-value = 0.029), as well as, presence of fasting procedure (P-value = 0.002). Multiple linear regression showed presence of fasting procedures to result in lower hypoglycaemic severity. ix Conclusion & Implications: Contributing factors of hypoglycaemic severity were found to be the total number of non-diabetic medications and presence of a fasting procedure. Although they proved statistical association with hypoglycaemic severity, no conclusive evidence was drawn to indicate their true cause. Future research is required to further explore how other demographic and clinical factors affect hypoglycaemic severity.
URI: http://scholarbank.nus.edu.sg/handle/10635/145857
Appears in Collections:Bachelor's Theses

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