Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/145854
Title: THE EFFECTS OF PHYSICAL ACTIVITY ON FATIGUE IN OLDER ADULTS AGED 50 AND ABOVE WITH CANCER DURING AND/OR AFTER CANCER THERAPY: A SYSTEMATIC REVIEW AND METAANALYSIS
Authors: KHADIJAH BINTE MOHD SANUSI
Keywords: Aged 50 and above, cancer-related fatigue, Physical activity
Issue Date: 21-Jun-2018
Citation: KHADIJAH BINTE MOHD SANUSI (2018-06-21). THE EFFECTS OF PHYSICAL ACTIVITY ON FATIGUE IN OLDER ADULTS AGED 50 AND ABOVE WITH CANCER DURING AND/OR AFTER CANCER THERAPY: A SYSTEMATIC REVIEW AND METAANALYSIS. ScholarBank@NUS Repository.
Abstract: Background: Highest incidence of cancer are among the older adult population aged 50 and above. One of the detrimental side effects experienced by those with cancer is cancer-related fatigue. Physical Activity (PA) produced beneficial effects in reducing cancer-related fatigue experienced during and/or after cancer therapy. Objectives: The objectives of this systematic review and meta-analysis was to synthesize the available literature to determine the effects of PA on cancer related-fatigue among older adults aged 50 and above during and/or after cancer therapy. Methods: Four databases (Cochrane, Embase, Medline, PubMed) was used to systematically search literature. Searching was performed from the year 2007 to 31st December 2017 and only Randomized Controlled Trials (RCT) was included. The Cochrane risk of bias tool and the GRADE framework was used to assess the overall quality of this review. Meta-analysis was performed using the RevMan software. Results: In total, 681 records were obtained from searching. Seven RCT was included in this review. According to the GRADE framework and risk of bias assessment, the overall quality of this review was low. From the meta-analysis, benefits of PA on cancer-related fatigue were seen among the intervention group compared to the control group. Lower levels of cancerrelated fatigue were also seen among prostate cancer patients. Finally, aerobic exercise and low intensity PA was observed to reduce cancer-related fatigue. Conclusion: In conclusion, PA appeared to have short-term beneficial effects to reduce cancerrelated fatigue among older adults aged 50 and above during and/or after cancer therapy. Recommendations: From the results obtained, PA is viewed as one of the essential nonpharmacological intervention to reduce cancer-related fatigue among older adults aged 50 and above. Steps are necessary to ensure safety and efficacy of PA. Long term effect of PA should be explored to better understand the effects of PA on cancer-related fatigue.efficacy of PA. Long term effect of PA should be explored to better understand the effects of PA on cancer-related fatigue. a better surgery experience for both parents and children.
URI: http://scholarbank.nus.edu.sg/handle/10635/145854
Appears in Collections:Bachelor's Theses (Restricted)

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