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https://scholarbank.nus.edu.sg/handle/10635/139100
| Title: | POST-TRANSLATIONAL MODIFICATIONS THAT INFLUENCE THE DNA REPAIR FUNCTION OF CYTOSOLIC FUMARASE | Authors: | DHARANIDHARAN RAMAMURTHY | ORCID iD: |  orcid.org/0000-0002-0485-4308 |
Keywords: | Fumarase, linker histone H1, post-translational modification, double-strand break, DNA repair. | Issue Date: | 25-Aug-2017 | Citation: | DHARANIDHARAN RAMAMURTHY (2017-08-25). POST-TRANSLATIONAL MODIFICATIONS THAT INFLUENCE THE DNA REPAIR FUNCTION OF CYTOSOLIC FUMARASE. ScholarBank@NUS Repository. | Abstract: | The study identified new post translational modifications to cytosolic fumarase and showed their effect on the enzymatic and DNA repair function of the enzyme. Furthermore the interaction with fumarate reductase and the linker histone H1 shown sheds light on a potential new mechanism by which cytosolic fumarase aids in double stranded DNA damage repair. | URI: | https://scholarbank.nus.edu.sg/handle/10635/139100 |
| Appears in Collections: | Ph.D Theses (Open) |
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|---|---|---|---|---|---|---|
| RamamurthyD.pdf | 3.05 MB | Adobe PDF | OPEN | None | View/Download |
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