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Title: Investigation of fluid flow through two-depth and two-width micro channels
Keywords: microfluidics, micro channel, micro reservoir, two-phase flow, flow resistance, flow simulation
Issue Date: 16-Feb-2004
Citation: RISHI JAIN (2004-02-16). Investigation of fluid flow through two-depth and two-width micro channels. ScholarBank@NUS Repository.
Abstract: The family of chips called micro total analysis systems (I?-TAS) and lab-on-chip (LOC) refers to microfluidics devices and their functional integration. The microfluidic aspect of I?-TAS and LOC deals with single phase or multi-phase fluid flow inside the micro channels of different geometries, shapes and architecture. A two-depth and two-width micro channel is introduced in which a micro-reservoir is placed between two micro channels namely the first channel, the depth of which is equal to the depth of micro reservoir and the shallow channel, the depth of which is approximately 1/120th to 1/20th of the depth of the micro reservoir. These kinds of micro channels are suitable for I?-TAS and LOC applications for they can be used for cell-cell separation, cell deformability tests, micro-filters, micro-reactors etc. Different architectures of these micro channels can be optimized for different applications. In this study, Computational Fluid Dynamics (CFD) two-phase flow simulations have been carried out to understand the performance of these micro channels in terms of pressure profiles and centerline velocity magnitude along the length of the channel, particle accumulation and path lines in the micro reservoir of the channel and the flow resistance of these micro channels. The effects of the position of the micro reservoir from the inlet, the depth of first channel, micro reservoir and shallow channel and the cross-section of the micro reservoir for different widths of first channel have been analyzed. Experimental studies have been carried out to examine the flow resistance of a two-depth two-width micro channel and a straight micro channel.
Appears in Collections:Master's Theses (Open)

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