Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/134591
Title: DEVELOPMENT AND UTILIZATION OF NOVEL IMAGE PROCESSING TECHNIQUES TO CHARACTERIZE THE CHOROID IN ASIANS
Authors: PREETI GUPTA
Keywords: Choroid, Choroidal thickness, Enhanced depth imaging,Spectral domain optical coherence tomography, Image processing techniques.
Issue Date: 20-Jul-2016
Source: PREETI GUPTA (2016-07-20). DEVELOPMENT AND UTILIZATION OF NOVEL IMAGE PROCESSING TECHNIQUES TO CHARACTERIZE THE CHOROID IN ASIANS. ScholarBank@NUS Repository.
Abstract: Despite the introduction of enhanced depth imaging technique of spectral domain optical coherence tomography it is still not a trivial task to image the choroid. Among various reasons, the most important are: poor visibility of the interface between the choroid and sclera (CSI) and manual measurements of choroidal thickness (CT) performed at few points around foveal centre, therefore, subjected to intra- and inter-operator biases not adequately reflective of the profile of entire choroid. Thus, there is a need for novel image processing techniques which can enhance the CSI, objectively and accurately define the CSI as well as measure CT and choroidal volume. In this dissertation we overcame the above challenges by our novel fully automated choroidal segmentation technique. To answer whether there exists any ethnic variation in CT among Asians and if there are differences in systemic and ocular risk factors of CT in different ethnic groups, we evaluated the distribution and determinants of CT and volume in a multi-ethnic population in Singapore. This research also provides a detailed morphological and vascular analysis of the choroid in various eye diseases.
URI: http://scholarbank.nus.edu.sg/handle/10635/134591
Appears in Collections:Ph.D Theses (Open)

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