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|Title:||Radioimmunoassay for serum gastrin in Singapore Chinese|
|Authors:||Ti, T.K. |
|Citation:||Ti, T.K., Yuen, R., Tan, W. (1981). Radioimmunoassay for serum gastrin in Singapore Chinese. Singapore Medical Journal 22 (1) : 12-15. ScholarBank@NUS Repository.|
|Abstract:||Fasting serum gastrin was determined by radioimmunoassay with the Dianabot kit (Tokyo) in 81 Chinese subjects. The mean fasting serum gastrin level in 43 duodenal ulcer patients (73 pg/ml) was higher than that in 18 control subjects (57 pg/ml) though the difference did not reach statistical significance. These levels fall within the range in Caucasians. The findings support the hypothesis that impaired auto-regulation of gastrin release in patients with duodenal ulcer by low antral pH is a contributing factor in duodenal ulcer diathesis. The mean fasting level in 19 gastric ulcer patients (68 pg/ml) was also higher than in the control subjects, but not significantly so. The infrequency of hypergastrinaemia in these gastric ulcer patients is probably due to associated antral gastritis.|
|Source Title:||Singapore Medical Journal|
|Appears in Collections:||Staff Publications|
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