Please use this identifier to cite or link to this item:
|Title:||Suppression of arterial pressure, heart rate and cardiac contractility following microinjection of kainic acid into the nucleus ambiguus of the rat|
|Citation:||Chan, S.H.H., Ong, B.T., Wong, P.T.H. (1984). Suppression of arterial pressure, heart rate and cardiac contractility following microinjection of kainic acid into the nucleus ambiguus of the rat. Neuroscience Letters 47 (1) : 57-62. ScholarBank@NUS Repository. https://doi.org/10.1016/0304-3940(84)90386-0|
|Abstract:||In pentobarbital anesthetized rats, unilateral microinjection (500 ng) of the selective perikaryal excitotoxin, kainic acid, into the nucleus ambiguus promoted a significant suppression of arterial pressure, heart rate and cardiac contractility. The degree of such cardiovascular depression followed the order of heart contractility reduction (50.7%) > hypotension (28.9%) > bradycardia (20.8%) at the end of a 60-min postinjection period. We concluded that the nucleus ambiguus may exert its control on cardiac activities by both negative chronotropic and inotropic effects on the heart.|
|Source Title:||Neuroscience Letters|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Mar 23, 2019
WEB OF SCIENCETM
checked on Mar 13, 2019
checked on Oct 18, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.