Please use this identifier to cite or link to this item: https://doi.org/10.1097/00004694-199803000-00005
Title: Treatment of growth arrest by transfer of cultured chondrocytes into physeal defects
Authors: Lee, E.H. 
Chen, F. 
Chan, J.
Bose, K. 
Issue Date: 1998
Source: Lee, E.H., Chen, F., Chan, J., Bose, K. (1998). Treatment of growth arrest by transfer of cultured chondrocytes into physeal defects. Journal of Pediatric Orthopaedics 18 (2) : 155-160. ScholarBank@NUS Repository. https://doi.org/10.1097/00004694-199803000-00005
Abstract: Chondrocytes were cultured from cartilage harvested from the iliac apophysis and knee joints of New Zealand White (NZW) rabbits. An experimental model for growth arrest was created by excising the medial half of the proximal growth plate of the tibia of 6-week-old NZW rabbits. The cultured chondrocytes were embedded in agarose and transferred into the growth-plate defect after excision of the physis. Transfer also was performed after excision of the bony bridge in established growth arrest. In both cases, growth arrest with angular deformation of the tibia was prevented. Histological studies confirmed the viability of the chondrocytes in the new host physis.
Source Title: Journal of Pediatric Orthopaedics
URI: http://scholarbank.nus.edu.sg/handle/10635/133849
ISSN: 02716798
DOI: 10.1097/00004694-199803000-00005
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