Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/133716
Title: Termination of second trimester pregnancy with laminaria and intramuscular 16 phenoxy-ω-17,18,19,20 tetranor PGE2 methylsuldonylamide (sulprostone) - A randomised study
Authors: Karim, S.M.M.
Ratnam, S.S. 
Kim, A.L.
Yeo, K.C.
Choo, H.T.
Issue Date: Feb-1982
Source: Karim, S.M.M., Ratnam, S.S., Kim, A.L., Yeo, K.C., Choo, H.T. (1982-02). Termination of second trimester pregnancy with laminaria and intramuscular 16 phenoxy-ω-17,18,19,20 tetranor PGE2 methylsuldonylamide (sulprostone) - A randomised study. Prostaglandins 23 (2) : 257-263. ScholarBank@NUS Repository.
Abstract: 16 phenoxy-ω-17,18,19,20 tetranor PGE2 methylsulfonylamide (Sulprostone) was used for termination of second trimester pregnancy in four groups of 30 patients. The drug was administered in intramuscular doses of either 0.5 mg four hourly or 1.0 mg 8 hourly. In two groups of 30 patients a medium size sterile laminaria was inserted into the cervical canal eight hours before the start of prostaglandin treatment. In the group treated with 1.0 mg sulprostone eight hourly, 96.7% of those with laminaria and 86.7% without laminaria aborted in respective mean times of 11.2 hrs and 17.5 hrs. All 30 patients (100%) in the laminaria group treated with 0.5 mg sulprostone four hourly aborted within 30 hours in a mean time of 10.4 hours compared with 26 patients (86.7%) in a mean time of 16.7 hours in the group without laminaria. One patient receiving 0.5 mg sulprostone four hourly (no laminaria) sustained a cervical tear requiring repair. The incidence of nausea, vomiting, diarrhoea, cold and shivering was low and similar in the four groups. © 1982.
Source Title: Prostaglandins
URI: http://scholarbank.nus.edu.sg/handle/10635/133716
ISSN: 00906980
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Page view(s)

11
checked on Jan 13, 2018

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.