Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/133623
Title: The use of the single radial haemolysis technique in the serological diagnosis of dengue and Japanese encephalitis virus infections
Authors: Chan, Y.C. 
Tan, H.C.
Tan, S.H.
Balachandran, K.
Issue Date: 1985
Source: Chan, Y.C., Tan, H.C., Tan, S.H., Balachandran, K. (1985). The use of the single radial haemolysis technique in the serological diagnosis of dengue and Japanese encephalitis virus infections. Bulletin of the World Health Organization 63 (6) : 1043-1053. ScholarBank@NUS Repository.
Abstract: The single radial haemolysis test for the serological diagnosis of suspected dengue and Japanese encephalitis virus infections uses crude virus antigens with a haemagglutinin titre of 1:320 or 1:640. The results, which may be read 3 hours after the addition of a patient's serum, showed a general agreement between this test and haemagglutination-inhibition tests in the number of case diagnoses that were confirmed. The antibody responses of individual patients shown by the two tests, however, were different, which suggests that the two tests may not be measuring the same antibody. The single radial haemolysis test can distinguish between dengue and Japanese encephalitis viruses using specific mouse hyperimmune sera. Tests on a limited number of sera from Japanese encephalitis patients also showed no cross-reactions with dengue virus antigens in those cases having a low-titred but significant fourfold antibody rise to Japanese encephalitis antigen.
Source Title: Bulletin of the World Health Organization
URI: http://scholarbank.nus.edu.sg/handle/10635/133623
ISSN: 00429686
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Page view(s)

4
checked on Jan 13, 2018

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.