Please use this identifier to cite or link to this item: https://doi.org/10.1016/0091-3057(91)90542-A
Title: The effects of d-amphetamine on the electrophysiological activity of the superior colliculus in the rat
Authors: Chee, S.-J. 
Keywords: arousal
d-amphetamine
EEG
hooded rats
illumination
locomotor activity
superior colliculus
Issue Date: 1991
Citation: Chee, S.-J. (1991). The effects of d-amphetamine on the electrophysiological activity of the superior colliculus in the rat. Pharmacology Biochemistry and Behavior 40 (2) : 215-220. ScholarBank@NUS Repository. https://doi.org/10.1016/0091-3057(91)90542-A
Abstract: The superior colliculus (SC) is thought to have an inhibitory effect on arousal (and hence activity) in rats when light is present. d-Amphetamine is believed to suppress this inhibition of the SC on arousal. The present study investigated the electrophysiological activity of the SC of the rat under the influence of d-amphetamine in both light and dark conditions. A single numerical arousal index value (AI) for the electrophysiological data obtained by dividing the frequency of the waves by the voltage over a specified interval was used. Results showed that light conditions decreased the AI of the SC. The AI was, however, not affected by d-amphetamine. Also, the electrophysiological activity of the SC showed spontaneous emissions of high-voltage (600 μV) alpha waves which generally occurred in two- to four-second bursts. Occurrence of this high-voltage activity was reduced by increasing doses of d-amphetamine.
Source Title: Pharmacology Biochemistry and Behavior
URI: http://scholarbank.nus.edu.sg/handle/10635/133446
ISSN: 00913057
DOI: 10.1016/0091-3057(91)90542-A
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