Please use this identifier to cite or link to this item:
https://doi.org/10.1002/ijc.2910180202
DC Field | Value | |
---|---|---|
dc.title | Impaired general cell mediated immune functions in vivo and in vitro in patients with nasopharyngeal carcinoma | |
dc.contributor.author | Chan, S.H. | |
dc.contributor.author | Chew, T.S. | |
dc.contributor.author | Goh, E.H. | |
dc.contributor.author | Simons, M.J. | |
dc.contributor.author | Shanmugaratnam, K. | |
dc.date.accessioned | 2016-12-19T06:48:40Z | |
dc.date.available | 2016-12-19T06:48:40Z | |
dc.date.issued | 1976 | |
dc.identifier.citation | Chan, S.H., Chew, T.S., Goh, E.H., Simons, M.J., Shanmugaratnam, K. (1976). Impaired general cell mediated immune functions in vivo and in vitro in patients with nasopharyngeal carcinoma. International Journal of Cancer 18 (2) : 139-144. ScholarBank@NUS Repository. https://doi.org/10.1002/ijc.2910180202 | |
dc.identifier.issn | 00207136 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/133250 | |
dc.description.abstract | General cell mediated immune (CMI) functions in NPC patients were investigated by the in vivo Mantoux and in vitro lymphocyte response to PHA assays. Thirty eight (50%) of 76 untreated NPC patients were hyporesponsive in the Mantoux assay compared to 27 (25%) of 110 control patients. Forty three (65.2%) of 66 untreated NPC patients also showed lymphocyte hyporesponsiveness to PHA compared to 15 (15.5%) of 97 control patients. Combined deficiencies were observed in 35 (42.2%) of 83 NPC patients compared to only 2 (3.3%) of 61 control patients. No difference in the frequency of immunodeficiency was observed between 'early' and 'late' disease patients. CMI functions of treated 'remission' NPC patients were found to be impaired to the same extent as those of untreated NPC patients. | |
dc.description.uri | http://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1002/ijc.2910180202 | |
dc.source | Scopus | |
dc.type | Article | |
dc.contributor.department | MICROBIOLOGY | |
dc.contributor.department | PATHOLOGY | |
dc.description.doi | 10.1002/ijc.2910180202 | |
dc.description.sourcetitle | International Journal of Cancer | |
dc.description.volume | 18 | |
dc.description.issue | 2 | |
dc.description.page | 139-144 | |
dc.description.coden | IJCNA | |
dc.identifier.isiut | A1976CB42400001 | |
Appears in Collections: | Staff Publications |
Show simple item record
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.