Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/133149
Title: EARLY LIFE RISK FACTORS OF MYOPIA IN CHILDREN
Authors: CHUA YU LIN, SHARON
Keywords: myopia, risk factors, spherical equivalent, axial length, children
Issue Date: 17-Aug-2016
Source: CHUA YU LIN, SHARON (2016-08-17). EARLY LIFE RISK FACTORS OF MYOPIA IN CHILDREN. ScholarBank@NUS Repository.
Abstract: Myopia is a significant public health concern due to its increasing prevalence over the past few decades. Studies have shown that children are developing myopia at younger ages and this is of great concern as early-onset myopes have increased risk of high myopia. High myopia is significantly associated with the development of ocular pathologies which may cause blindness. Therefore, it is important to understand the risk factors associated with early-onset myopia in young children. In the Growing Up in Singapore Towards Healthy Outcomes (GUSTO) cohort, it was found that having myopic parents and exposure to passive smoke from birth to <6months were risk factors for early-onset myopia in 3-year old children. From the Singapore Cohort Of the Risk factors for Myopia (SCORM) cohort, we showed that younger age of myopia onset was associated with high myopia at 11 years of age. Thus, the risk factors of early-onset myopia may be predominantly genetic with the possible influence of environmental factors at an early age such as passive smoke exposure. Future trials to delay myopia progression could focus on children with younger age of myopia onset.
URI: http://scholarbank.nus.edu.sg/handle/10635/133149
Appears in Collections:Ph.D Theses (Open)

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