Please use this identifier to cite or link to this item: https://doi.org/10.1097/00129492-200405000-00005
Title: Invasive middle ear cholesterol granuloma involving the basal turn of the cochlea with profound sensorineural hearing loss
Authors: Murugasu, E. 
Yong, T.T.
Yoon, C.P.
Keywords: Cholesterol granuloma
Cochlear invasion
Middle ear
Profound deafness
Issue Date: May-2004
Citation: Murugasu, E., Yong, T.T., Yoon, C.P. (2004-05). Invasive middle ear cholesterol granuloma involving the basal turn of the cochlea with profound sensorineural hearing loss. Otology and Neurotology 25 (3) : 231-235. ScholarBank@NUS Repository. https://doi.org/10.1097/00129492-200405000-00005
Abstract: Study Design: A retrospective surgical case review. Setting: A tertiary-care, university teaching hospital. Patients: The authors describe a unique case operated on for a middle ear cholesterol granuloma, which had invaded the cochlea and vestibule causing profound sensorineural deafness. Interventions: Extended radical mastoidectomy and labyrinthectomy with musculofascial seal. Results: Successful postoperative outcome with no recurrence seen after 2 years of follow up. Conclusion: To the authors' knowledge, this is the first reported case of a primary middle ear cholesterol granuloma with direct invasion into the cochlea. Such invasion of the otic capsule by cholesterol granulomas is rare and presents a diagnostic challenge to the attending otologist and radiologist, Salient points of the case history, pathogenesis, imaging studies, histopathology, and management are presented with a review of the current literature.
Source Title: Otology and Neurotology
URI: http://scholarbank.nus.edu.sg/handle/10635/133047
ISSN: 15317129
DOI: 10.1097/00129492-200405000-00005
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