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|Title:||Higher order ocular aberrations in eyes with myopia in a Chinese population|
|Source:||Wei, R.H., Lim, L., Chan, W.K., Tan, D.T.H. (2006-09). Higher order ocular aberrations in eyes with myopia in a Chinese population. Journal of Refractive Surgery 22 (7) : 695-702. ScholarBank@NUS Repository.|
|Abstract:||PURPOSE: To describe the characteristics of higher order ocular aberrations of adult Chinese eyes with myopia. METHODS: Higher order aberrations in consecutive right eyes of 166 Chinese patients with myopia who enrolled for preoperative assessment for LASIK were retrospectively reviewed. Wavefront aberrations were measured with the Bausch & Lomb Zywave over a 6-mm dilated pupil. The correlations between higher order aberrations and myopia, astigmatism, and age, respectively, were analyzed. RESULTS: Mean patient age was 32.1±6.2 years, the mean refractive error was sphere -5.23±1.79 diopters (D) and cylinder -1.29±0.98 D. The mean of the total higher order root-mean-square (RMS) (third to fifth order) was 0.49±0.16 μm. Third-order RMS was largest (mean 0.37±0.16 μm), followed by fourth-order RMS (mean 0.29±0.11 μm). For individual higher order Zernike coefficients, spherical aberration (C4 0) predominated with a mean of 0.23±0.14 μm. No correlation was found between total higher order RMS and myopia or between total higher order RMS and age. Small but statistically significant relationships were found in the following groups: age and vertical primary coma (C3 -1) (r=-0.206, P=.008); age and spherical aberration (C4 0) (r=0.196, P=.012); and myopia and horizontal trefoil (C3 3) (r=-0.158, P=.042). CONCLUSIONS: Higher order aberrations varied among individuals with myopia. Third-order RMS was the predominant higher order aberration. Spherical aberration and vertical primary coma increased slightly with age. Our study helps establish ocular aberration standards for Chinese refractive surgery candidates.|
|Source Title:||Journal of Refractive Surgery|
|Appears in Collections:||Staff Publications|
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