Please use this identifier to cite or link to this item: https://doi.org/10.1007/BF01300078
Title: Helicobacter pylori and gastric acid output in peptic ulcer disease
Authors: Kang, J.Y. 
Wee, A. 
Keywords: duodenal ulcer
gastric ulcer
gastritis
Issue Date: Jan-1991
Citation: Kang, J.Y., Wee, A. (1991-01). Helicobacter pylori and gastric acid output in peptic ulcer disease. Digestive Diseases and Sciences 36 (1) : 5-9. ScholarBank@NUS Repository. https://doi.org/10.1007/BF01300078
Abstract: Helicobacter pylori is associated with peptic ulcer, and a causal relationship has been postulated. We investigated the association between Helicobacter pylori and gastric acid output. Two hundred forty-one patients were studied: 173 with duodenal ulcer, 51 with gastric ulcer (41 corpus, 10 prepyloric), and 17 with combined gastric and duodenal ulcer. In 194 patients (80%), Helicobacter pylori could be demonstrated histologically from gastric antral biopsies. The presence or absence of Helicobacter pylori was not influenced by age, sex, or use of tobacco or analgesics. Patients with duodenal ulcer or combined gastric and duodenal ulcer had similar gastric acid outputs irrespective of the presence or absence of Helicobacter pylori. However, gastric ulcer patients with Helicobacter had higher basal and maximal acid outputs when compared to patients without Helicobacter (mean basal output: 4.1 mmol/hr vs 2.4, P
Source Title: Digestive Diseases and Sciences
URI: http://scholarbank.nus.edu.sg/handle/10635/132652
ISSN: 01632116
DOI: 10.1007/BF01300078
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