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https://scholarbank.nus.edu.sg/handle/10635/13264
DC Field | Value | |
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dc.title | Monte Carlo simulation of a supercoiled double-stranded DNA model | |
dc.contributor.author | CHUNG WENG YEW | |
dc.date.accessioned | 2010-04-08T10:31:28Z | |
dc.date.available | 2010-04-08T10:31:28Z | |
dc.date.issued | 2008-06-02 | |
dc.identifier.citation | CHUNG WENG YEW (2008-06-02). Monte Carlo simulation of a supercoiled double-stranded DNA model. ScholarBank@NUS Repository. | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/13264 | |
dc.description.abstract | An efficient Monte Carlo Metropolis simulation [Monte Carlo et al, 1953] wasconducted on the double stranded DNA model proposed by [Zhang et al, 2000]. Themodel was mathematically discussed in detail and the calculation time for the energycomponents were improved. The mathematical characteristic of the writhe calculationwas also examined and a fast algorithm which reduces the writhe calculation by 45-55% was presented. The method was verified with the conventional algorithm and thecalculated writhe was found to be accurate within usable limits. The force versusextension and supercoiling degree versus extension relationships of the model werealso investigated and verified with the experimental results published by [Strick et al,1998]. The results obtained from the simulation coincide reasonably with theexperimental measurements. | |
dc.language.iso | en | |
dc.subject | Monte Carlo DNA Double-Stranded Writhe Linking | |
dc.type | Thesis | |
dc.contributor.department | CIVIL ENGINEERING | |
dc.contributor.supervisor | LIAW CHIH YOUNG | |
dc.description.degree | Master's | |
dc.description.degreeconferred | MASTER OF ENGINEERING | |
dc.identifier.isiut | NOT_IN_WOS | |
Appears in Collections: | Master's Theses (Open) |
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Files in This Item:
File | Description | Size | Format | Access Settings | Version | |
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1. Chapter - Cover & Title.pdf | 15.58 kB | Adobe PDF | OPEN | None | View/Download | |
2. Chapter i - Acknowledgements.pdf | 11.18 kB | Adobe PDF | OPEN | None | View/Download | |
3. Chapter ii - Table of Contents.pdf | 28.9 kB | Adobe PDF | OPEN | None | View/Download | |
4. Chapter iii - Summary.pdf | 23.55 kB | Adobe PDF | OPEN | None | View/Download | |
5. Chapter iv - List of Tables.pdf | 13.58 kB | Adobe PDF | OPEN | None | View/Download | |
6. Chapter v - List of Figures.pdf | 26.29 kB | Adobe PDF | OPEN | None | View/Download | |
7. Chapter vi - References.pdf | 25.57 kB | Adobe PDF | OPEN | None | View/Download | |
8. Chapter 1 - Introduction.pdf | 37.73 kB | Adobe PDF | OPEN | None | View/Download | |
9. Chapter 2 - Statistical Mechanics.pdf | 164.85 kB | Adobe PDF | OPEN | None | View/Download | |
10. Chapter 3 - DNA Model.pdf | 152.49 kB | Adobe PDF | OPEN | None | View/Download | |
11. Chapter 4 - Move Generations.pdf | 100.92 kB | Adobe PDF | OPEN | None | View/Download | |
12. Chapter 5 - Supercoiling Degree of DNA.pdf | 459.69 kB | Adobe PDF | OPEN | None | View/Download | |
13. Chapter 6 - MC Metropolis Simulation.pdf | 154.64 kB | Adobe PDF | OPEN | None | View/Download | |
14. Chapter 7 - Conclusion.pdf | 32.43 kB | Adobe PDF | OPEN | None | View/Download | |
15. Chapter A - Simulation Flow Chart.pdf | 33.35 kB | Adobe PDF | OPEN | None | View/Download |
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