Please use this identifier to cite or link to this item: https://doi.org/10.1111/j.1471-0528.2002.01424.x
Title: Microvascular changes in the peripheral microcirculation of women with chronic pelvic pain due to congestion
Authors: Foong, L.C. 
Gamble, J.
Sutherland, I.A.
Beard, R.W.
Issue Date: Aug-2002
Source: Foong, L.C., Gamble, J., Sutherland, I.A., Beard, R.W. (2002-08). Microvascular changes in the peripheral microcirculation of women with chronic pelvic pain due to congestion. BJOG: An International Journal of Obstetrics and Gynaecology 109 (8) : 867-873. ScholarBank@NUS Repository. https://doi.org/10.1111/j.1471-0528.2002.01424.x
Abstract: Objective: Pelvic venous congestion is a common finding in women with chronic pelvic pain. While the pathophysiology of this condition is poorly understood, there are clear indications that it involves vascular dysfunction. The present studies sought abnormalities in microvascular function in these patients. Design: Prospective longitudinal study. Setting: A teaching hospital tertiary referral. Population: Eighteen women with pelvic congestion and 13 nomal women. Methods: Parameters of microcirculatory function were measured in the calves of women using venous congestion plethysmography during the midfollicular and midluteal phases of the menstrual cycle. The women with pelvic congestion were studied again after treatment for the condition. Main outcome measures: Isovolumetric venous pressure, microvascular filtration capacity and limb blood flow. Results: Of the measured parameters of microvascular function, only isovolumetric venous pressure (Pvi) was significantly higher in women with congestion when compared to the controls during the same phase of the cycle. There were no menstrual cycle related differences in any of the other measured parameters in either patients or controls. Following successful treatment for the condition, values of Pvi in women with pelvic congestion were significantly reduced, achieving a level similar to that observed in the controls. Conclusion: The observed changes in Pvi suggest that this parameter is intimately associated with the pathophysiology of pelvic congestion. The increase in Pvi, without alterations in other measured microvascular parameters, may be attributable to systemic increases in postcapillary resistance secondary to neutrophil activation. These findings support the notion of systemic microvascular dysfunction in these women.
Source Title: BJOG: An International Journal of Obstetrics and Gynaecology
URI: http://scholarbank.nus.edu.sg/handle/10635/132570
ISSN: 14700328
DOI: 10.1111/j.1471-0528.2002.01424.x
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

6
checked on Jan 17, 2018

Page view(s)

9
checked on Jan 14, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.