Please use this identifier to cite or link to this item:
|Title:||Micro-insemination sperm transfer (MIST) and its application to male subfertility: current strategies to improve results.|
|Authors:||Ng, S.C. |
|Source:||Ng, S.C., Bongso, T.A., Liow, S.L., Edirisinghe, R., Ratnam, S.S. (1992-07). Micro-insemination sperm transfer (MIST) and its application to male subfertility: current strategies to improve results.. Annals of the Academy of Medicine Singapore 21 (4) : 561-564. ScholarBank@NUS Repository.|
|Abstract:||It can be difficult to achieve a pregnancy for patients with severe male factor subfertility. Hence, micro-manipulation techniques, have been applied to this problem. Direct deposition of sperm into the oocyte under the zona (micro-insemination sperm transfer, MIST) has improved the fertilisation rates, but pregnancy rates have been very low. This paper describes the possible new strategies to improve the technique currently. They include methods to improve sperm recovery, to improve acrosome reaction, to improve the quality of embryos by using co-cultures and to wait for good cleavage before transfer, and to improve luteal phase support. There are also many new techniques being developed which may contribute to further pregnancy successes. They include the use of electro-fusion, laser-fusion and the Xenopus cell-free system.|
|Source Title:||Annals of the Academy of Medicine Singapore|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jan 14, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.