Please use this identifier to cite or link to this item: https://doi.org/10.1105/tpc.106.041178
Title: Maintenance of DNA methylation during the arabidopsis life cycle is essential for parental imprinting
Authors: Jullien, P.E.
Kinoshita, T.
Ohad, N.
Berger, F. 
Issue Date: Jun-2006
Source: Jullien, P.E., Kinoshita, T., Ohad, N., Berger, F. (2006-06). Maintenance of DNA methylation during the arabidopsis life cycle is essential for parental imprinting. Plant Cell 18 (6) : 1360-1372. ScholarBank@NUS Repository. https://doi.org/10.1105/tpc.106.041178
Abstract: Imprinted genes are expressed predominantly from either their paternal or their maternal allele. To date, all imprinted genes identified in plants are expressed in the endosperm. In Arabidopsis thaliana, maternal imprinting has been clearly demonstrated for the Polycomb group gene MEDEA (MEA) and for FWA. Direct repeats upstream of FWA are subject to DNA methylation. However, it is still not clear to what extent similar cis-acting elements may be part of a conserved molecular mechanism controlling maternally imprinted genes. In this work, we show that the Polycomb group gene FERTILIZATION-INDEPENDENT SEED2 (FIS2) is imprinted. Maintenance of FIS2 imprinting depends on DNA methylation, whereas loss of DNA methylation does not affect MEA imprinting. DNA methylation targets a small region upstream of FIS2 distinct from the target of DNA methylation associated with FWA. We show that FWA and FIS2 imprinting requires the maintenance of DNA methylation throughout the plant life cycle, including male gametogenesis and endosperm development. Our data thus demonstrate that parental genomic imprinting in plants depends on diverse cis-elements and mechanisms dependent or independent of DNA methylation. We propose that imprinting has evolved under constraints linked to the evolution of plant reproduction and not by the selection of a specific molecular mechanism. © 2006 American Society of Plant Biologists.
Source Title: Plant Cell
URI: http://scholarbank.nus.edu.sg/handle/10635/131431
ISSN: 10404651
DOI: 10.1105/tpc.106.041178
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

202
checked on Jan 17, 2018

WEB OF SCIENCETM
Citations

190
checked on Dec 5, 2017

Page view(s)

10
checked on Jan 14, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.