Please use this identifier to cite or link to this item:
|Title:||Interaction of kunjin virus with octyl-D-glucoside extracted Vero cell plasma membrane|
|Authors:||Sankaran, D. |
|Citation:||Sankaran, D., Lau, L.C.L., Ng, M.L. (1997-01). Interaction of kunjin virus with octyl-D-glucoside extracted Vero cell plasma membrane. Journal of Virological Methods 63 (1-2) : 167-173. ScholarBank@NUS Repository.|
|Abstract:||Initial experiments using whole cells have shown that there were specific and saturable interactions between kunjin (KUN) virus and receptor molecules on the Vero cell surfaces. Solubilisation of Vero cell plasma membranes with octyl-D-glucoside (OG) yielded an extract which also interacted specifically with KUN virus. This was proven using electron microscopy. When the virus-OG-extract complex was exposed onto Vero cell monolayers, no KUN virus was observed to enter into the whole cells. This would imply that there was virus-receptor interaction with the OG-extract leaving no free virus to attach to the whole cells. The attachment kinetics of KUN virus was studied further using the Scatchard analysis which indicated the involvement of more than one interactive macromolecule in the attachment event.|
|Source Title:||Journal of Virological Methods|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on May 18, 2018
WEB OF SCIENCETM
checked on Dec 26, 2018
checked on Dec 14, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.