Please use this identifier to cite or link to this item:
https://scholarbank.nus.edu.sg/handle/10635/131239
DC Field | Value | |
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dc.title | Pharmacokinetics of oral salbutamol controlled-release in Asian patients with asthma | |
dc.contributor.author | Tan, W.C. | |
dc.contributor.author | Lee, H.S. | |
dc.date.accessioned | 2016-11-28T10:17:52Z | |
dc.date.available | 2016-11-28T10:17:52Z | |
dc.date.issued | 1991 | |
dc.identifier.citation | Tan, W.C., Lee, H.S. (1991). Pharmacokinetics of oral salbutamol controlled-release in Asian patients with asthma. European Journal of Clinical Pharmacology 41 (5) : 495-496. ScholarBank@NUS Repository. | |
dc.identifier.issn | 00316970 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/131239 | |
dc.description.abstract | Using a double blind, double dummy crossover design, single dose and steady state pharmacokinetics of oral controlled release (SCR) salbutamol 4 mg and 8 mg tablets b.d. has been studied in 8 Asian patients. Plasma salbutamol was measured over 12 h. In 8 patients the single dose mean C(max) was 4.2 ng · ml-1 and 7.7 ng · ml-1 after 4 and 8 mg, respectively. In 5 patients the steady state mean C(max), C(min) and t(max) were S.1 ng · ml-1 and 4.7 ng · ml-1 and 6 h for the 4 mg tablets and 14.1 ng · ml-1 and 7.1 ng · ml-1 and 4 h for the 8 mg tablets. It is concluded that both doses of SCR show features of controlled release and that they produced a relatively constant plasma level of salbutamol in Asian patients. | |
dc.source | Scopus | |
dc.subject | Asians, pharmacokinetics | |
dc.subject | asthma, salbutamol | |
dc.type | Article | |
dc.contributor.department | MEDICINE | |
dc.contributor.department | PHARMACOLOGY | |
dc.description.sourcetitle | European Journal of Clinical Pharmacology | |
dc.description.volume | 41 | |
dc.description.issue | 5 | |
dc.description.page | 495-496 | |
dc.description.coden | EJCPA | |
dc.identifier.isiut | NOT_IN_WOS | |
Appears in Collections: | Staff Publications |
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