Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/131170
Title: Preoxygenation techniques: The value of nitrous oxide
Authors: Khoo, S.T. 
Woo, M. 
Kumar, A. 
Issue Date: 1993
Source: Khoo, S.T., Woo, M., Kumar, A. (1993). Preoxygenation techniques: The value of nitrous oxide. Acta Anaesthesiologica Scandinavica 37 (1) : 23-25. ScholarBank@NUS Repository.
Abstract: Changes in arterial oxygen saturation during induction of anaesthesia and intubation were studied using the pulse oximeter. Seventy-five young ASA I patients undergoing elective uncomplicated surgery were divided equally into three groups. The patients were preoxygenated with 100% oxygen, 50% oxygen: 50% nitrous oxide or 30% oxygen: 70% nitrous oxide for 1 min. All were then induced with thiopentone, paralysed with suxamethonium and orally intubated. Arterial oxygen saturations were continuously recorded by a separate investigator. All groups showed similar arterial desaturation during suxamethonium-induced apnoea and intubation, but the degree of desaturation was not clinically significant and no patient showed clinical signs of hypoxaemia. Preoxygenation with mixtures of oxygen and nitrous oxide can hasten the build-up of alveolar nitrous oxide concentration and help to smooth induction without compromising oxygenation of patients.
Source Title: Acta Anaesthesiologica Scandinavica
URI: http://scholarbank.nus.edu.sg/handle/10635/131170
ISSN: 00015172
Appears in Collections:Staff Publications

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