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|Title:||Intramuscular administration of 16 phenoxy ω 17,18,19, 20 tetranor PGE2 methyl sulfonylamide for pre-operative cervical dilatation in first trimester nulliparae|
|Citation:||Karim, S.M.M., Rancheran, A., Wun, W., Ho, T.H., Ratnam, S.S. (1978-07). Intramuscular administration of 16 phenoxy ω 17,18,19, 20 tetranor PGE2 methyl sulfonylamide for pre-operative cervical dilatation in first trimester nulliparae. Prostaglandines and Medicine 1 (1) : 71-75. ScholarBank@NUS Repository.|
|Abstract:||A single Intramuscular dose of 500 μg 16 phenoxy ω 17,18,19, 20 tetranor PGE2 methyl sulfonylamide was used for cervical dilatation prior to vacuum aspiration in 80 first trimester nulliparae. Three hours after prostaglandin administration the cervix had dilated to 8 mm or more in 60 patients (75%). The uterus was evacuated in these patients without mechanical dilatation of the cervix. In the remaining 20 patients the cervix had dilated 4 to 7 mm. Further mechanical dilatation to 8 mm was carried out easily in most of these patients. Side effects included pain requiring analgesic (3 patients), vomiting (4 patients) and transient pyrexia ( >1°C, 2 patients). There were no complications or damage to the uterus or the cervix during evacuation of the uterus. © 1978.|
|Source Title:||Prostaglandines and Medicine|
|Appears in Collections:||Staff Publications|
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