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|Title:||Unravelling the mystery in a case of persistent ACTH-independent Cushing's syndrome|
Nodular adrenocortical disease
|Source:||Ling, C.L., Tan, L.H.C., Rajasoorya, C. (2006-12). Unravelling the mystery in a case of persistent ACTH-independent Cushing's syndrome. Annals of the Academy of Medicine Singapore 35 (12) : 892-896. ScholarBank@NUS Repository.|
|Abstract:||Introduction: We present a rare variety of adrenocorticotrophic hormone (ACTH)-independent Cushing's syndrome known as primary pigmented nodular adrenocortical disease (PPNAD). Clinical Picture: The patient initially underwent unilateral adrenalectomy for what was thought to be a left adrenal adenoma. Outcome: Partial resolution of symptoms and demonstrable persistent hypercortisolism after surgery prompted further evaluation with findings leading to the diagnosis of Carney complex. A review of the adrenal histology was consistent with PPNAD. Conclusion: This entity of PPNAD, which has rarely been reported in Asians, forms part of the Carney complex. The diagnosis may not be simple and straightforward, as illustrated in this patient.|
|Source Title:||Annals of the Academy of Medicine Singapore|
|Appears in Collections:||Staff Publications|
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