The CCK2 agonist BC-264 decreases predatory fear freezing at high but not low dosages in PVG hooded rats during initial exposure to a cat

Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.peptides.2008.12.013

Title:	The CCK2 agonist BC-264 decreases predatory fear freezing at high but not low dosages in PVG hooded rats during initial exposure to a cat
Authors:	McLachlan, C.S. Farook, J.M. Daugé, V. Wong, P.T.
Keywords:	CCK Predatory fear PVG hooded rat
Issue Date:	Apr-2009
Citation:	McLachlan, C.S., Farook, J.M., Daugé, V., Wong, P.T. (2009-04). The CCK2 agonist BC-264 decreases predatory fear freezing at high but not low dosages in PVG hooded rats during initial exposure to a cat. Peptides 30 (4) : 808-809. ScholarBank@NUS Repository. https://doi.org/10.1016/j.peptides.2008.12.013
Abstract:	BC-264 a CCK2 agonist reverses chronically developed habituated predatory fear freezing behavior in PVG hooded rats. However, the acute effects of BC264 have not been previously examined. The effects of BC-264 (0.1-30 μg/kg) on the mean percentage of PVG hooded rat freezing during an initial first time 20 min cat exposure were calculated. At higher doses (15 or 30 μg/kg) but not lower doses (0.1-1 μg/kg) BC264 statistically significantly decreased freezing compared to control (p < 0.001). © 2009 Elsevier Inc. All rights reserved.
Source Title:	Peptides
URI:	http://scholarbank.nus.edu.sg/handle/10635/130079
ISSN:	01969781
DOI:	10.1016/j.peptides.2008.12.013
Appears in Collections:	Staff Publications

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