Please use this identifier to cite or link to this item: https://doi.org/10.1161/STROKEAHA.109.559435
Title: Retinal vascular caliber and extracranial carotid disease in patients with acute ischemic stroke: The multi-centre retinal stroke (mcrs) study
Authors: De Silva, D.A. 
Liew, G.
Wong, M.-C.
Chang, H.-M. 
Chen, C. 
Wang, J.J.
Baker, M.L.
Hand, P.J.
Rochtchina, E.
Liu, E.Y.
Mitchell, P.
Lindley, R.I.
Wong, T.Y. 
Keywords: Carotid disease
Ischemic stroke
Retinal vessel caliber
Issue Date: Dec-2009
Source: De Silva, D.A., Liew, G., Wong, M.-C., Chang, H.-M., Chen, C., Wang, J.J., Baker, M.L., Hand, P.J., Rochtchina, E., Liu, E.Y., Mitchell, P., Lindley, R.I., Wong, T.Y. (2009-12). Retinal vascular caliber and extracranial carotid disease in patients with acute ischemic stroke: The multi-centre retinal stroke (mcrs) study. Stroke 40 (12) : 3695-3699. ScholarBank@NUS Repository. https://doi.org/10.1161/STROKEAHA.109.559435
Abstract: Background and Purpose-Previous studies show that both retinal vascular caliber and carotid disease predict incident stroke in the general population, but the exact relationship between these 2 microvascular and macrovascular structural risk factors is unclear. We studied the relationship between retinal vascular caliber and carotid disease in patients presenting with acute ischemic stroke. Methods-We conducted a cross-sectional study of patients with acute ischemic stroke recruited from 3 centers (Melbourne, Sydney, Singapore). The caliber of retinal arterioles and venules was measured from digital retinal photographs. Severe extracranial carotid disease was defined as stenosis 75% or occlusion determined by carotid Doppler using North American Symptomatic Carotid Endarterectomy Trial-based criteria. Results-Among the 1029 patients with acute stroke studied, 7% of the population had severe extracranial carotid disease. Retinal venular caliber was associated with ipsilateral severe carotid disease (P
Source Title: Stroke
URI: http://scholarbank.nus.edu.sg/handle/10635/130029
ISSN: 00392499
DOI: 10.1161/STROKEAHA.109.559435
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