Please use this identifier to cite or link to this item: https://doi.org/10.1097/MOL.0b013e328304b681
Title: Clinical significance of apolipoprotein A5
Authors: Tai, E.S. 
Ordovas, J.M.
Keywords: Apolipoprotein A-V
Cardiovascular disease
Diet
Gene-environment interaction
Pharmacogenomics
Plasma lipids
Issue Date: Aug-2008
Citation: Tai, E.S., Ordovas, J.M. (2008-08). Clinical significance of apolipoprotein A5. Current Opinion in Lipidology 19 (4) : 349-354. ScholarBank@NUS Repository. https://doi.org/10.1097/MOL.0b013e328304b681
Abstract: Apolipoprotein A-V has an important role in lipid metabolism, specifically for triglyceride-rich lipoproteins. However, its mechanism of action is still poorly understood. Clinical significance at present comes largely from genetic studies showing a consistent association with plasma triglyceride concentrations. Moreover, the effects of common genetic variants on triglyceride concentrations and disease risk are further modulated by other factors such as diet, pharmacological interventions and BMI. Therefore, these genetic variants could be potentially used to predict cardiovascular disease risk and individualize therapeutic options to decrease cardiovascular disease risk. © 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins.
Source Title: Current Opinion in Lipidology
URI: http://scholarbank.nus.edu.sg/handle/10635/129736
ISSN: 09579672
DOI: 10.1097/MOL.0b013e328304b681
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